一抗
二抗
亲和凝胶及免疫磁珠
蛋白质定量试剂盒
蛋白质
规格：
查看说明书| Product Name: | Vcam1 Polyclonal Antibody |
| Cat No.: | D-AB-10152L |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse,Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB 1:500-1:1000 |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Antigen Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
| Immunogen: | Recombinant Rat Vcam1 protein expressed by Mammalian |
| Calculated Molecular Weight: | 81 kDa |
| Observed Molecular Weight: | 75-100 kDa |
| Background: | Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex(MHC) class-I presentation. |
| Category: | Primary Ab |
引用文献
