Cat No.: D-AB-10181L

规格：

Product Name:	LUM Polyclonal Antibody
Cat No.:	D-AB-10181L
Clonality:	Polyclonal
Species Reactivity:	Human,Mouse,Rat
Tested Applications:	WB
Recommended Dilution:	WB 1:500-1:1000
Format:	Liquid
Source:	Rabbit
Purification Method:	Antigen Affinity Purification
Isotype:	IgG
Conjugate:	Unconjugated
Storage:	Store at -20℃. Avoid freeze / thaw cycles.
Immunogen:	Recombinant Human LUM protein expressed by E.coli
Calculated Molecular Weight:	38kDa
Observed Molecular Weight:	50kDa
Background:	Lumican (LUM), a member of the small leucine-rich proteoglycan (SLRP) family, is one of the major extracellular components in interstitial collagenous matrices of the corneal stroma, aorta, skin, skeletal muscle, lung, kidney, bone, cartilage, and intervertebral discs. SLRPs constitute an important fraction of noncollagenous extracellular matrix proteins and have important effects on cell behavior. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and may exist as a glycoprotein in the connective tissues of other organs. Posttranslational modifications lumican goes through can increase its apparent molecular weight to 50-90 kDa. Studies show that lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation.
Category:	Primary Ab

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