Product Name: | LMNA Polyclonal Antibody |
Cat No.: | D-AB-10192L |
Clonality: | Polyclonal |
Species Reactivity: | Human,Mouse |
Tested Applications: | WB |
Recommended Dilution: | WB 1:500-1:1000 |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Antigen Affinity Purification |
Isotype: | IgG |
Conjugate: | Unconjugated |
Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
Immunogen: | Recombinant Human LMNA protein expressed by E.coli |
Calculated Molecular Weight: | 63,64,65,69,71,74 kDa |
Observed Molecular Weight: | 71,74 kDa |
Background: | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. |
Category: | Primary Ab |
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