Cat No.: D-AB-10209L

规格：

Product Name:	Serpina1 Polyclonal Antibody
Cat No.:	D-AB-10209L
Clonality:	Polyclonal
Species Reactivity:	Human,Mouse,Rat
Tested Applications:	WB
Recommended Dilution:	WB 1:500-1000
Format:	Liquid
Source:	Rabbit
Purification Method:	Antigen Affinity Purification
Isotype:	IgG
Conjugate:	Unconjugated
Storage:	Store at -20℃. Avoid freeze / thaw cycles.
Immunogen:	Recombinant Rat Serpina1 protein expressed by E.coli
Calculated Molecular Weight:	46kDa
Observed Molecular Weight:	43kDa,50kDa
Background:	SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT),which is a serine protease inhibitor whose targets include elastase,plasmin,thrombin,trypsin,chymotrypsin,and plasminogen activator. AAT is a glycoprotein synthesized primarily by hepatocytes,with smaller amountssynthesized by intestinal epithelial cells,neutrophils,pulmonary alveolar cells and macrophages. AAT is the most abundant,endogenous serine protease inhibitor in blood circulation and it has been implicated in regulating vital fluid phase biological events such as blood coagulation,fibrinolysis,complement activation,apoptosis,reproduction,tumor progression and inflammatory response. The primary function of AAT is thought to be the inactivation of neutrophil elastase and other endogenous serine proteases. Defects in SERPINA1 can cause emphysema or liver disease.
Category:	Primary Ab

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