一抗
二抗
亲和凝胶及免疫磁珠
蛋白质定量试剂盒
蛋白质
规格：
查看说明书| Product Name: | E-Cadherin Polyclonal Antibody |
| Cat No.: | D-AB-10198L |
| Clonality: | Polyclonal |
| Species Reactivity: | Human,Mouse,Rat |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB 1:500-1:1000 |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Antigen Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
| Immunogen: | Recombinant Human CDH1 protein expressed by E.coli |
| Calculated Molecular Weight: | 97kDa |
| Observed Molecular Weight: | 135kDa |
| Gene ID (NCBI): | 999 |
| Background: | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. |
| Category: | Primary Ab |
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