Cat No.: D-AB-10195L

规格：

Product Name:	TIMP1 Polyclonal Antibody
Cat No.:	D-AB-10195L
Clonality:	Polyclonal
Species Reactivity:	Mouse
Tested Applications:	WB
Recommended Dilution:	WB 1:500-1:1000
Format:	Liquid
Source:	Rabbit
Purification Method:	Antigen Affinity Purification
Isotype:	IgG
Conjugate:	Unconjugated
Storage:	Store at -20℃. Avoid freeze / thaw cycles.
Immunogen:	Recombinant Mouse Timp1 protein expressed by E.coli
Calculated Molecular Weight:	23kDa
Observed Molecular Weight:	30kDa
Gene ID (NCBI):	21857
Background:	This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Category:	Primary Ab

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