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CST3 Polyclonal Antibody

Cat No.: D-AB-10163L
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Product Name: CST3 Polyclonal Antibody
Cat No.: D-AB-10163L
Clonality: Polyclonal
Species Reactivity: Human,Mouse,Rat
Tested Applications: WB,IHC
Recommended Dilution: WB:1:500-1:1000,IHC 1:250-1:500
Format: Liquid
Source: Rabbit
Purification Method: Antigen Affinity Purification
Isotype: IgG
Conjugate: Unconjugated
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human CST3 protein expressed by E.coli
Calculated Molecular Weight: 15 kDa
Observed Molecular Weight: 15 kDa
Gene ID (NCBI): 1471
Background: Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration,shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions,establishing its role in vascular disease. In addition,this protein has been shown to have an antimicrobial function,inhibiting the replication of herpes simplex virus.
Category: Primary Ab
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