Product Name: | CST3 Polyclonal Antibody |
Cat No.: | D-AB-10163L |
Clonality: | Polyclonal |
Species Reactivity: | Human,Mouse,Rat |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB:1:500-1:1000,IHC 1:250-1:500 |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Antigen Affinity Purification |
Isotype: | IgG |
Conjugate: | Unconjugated |
Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
Immunogen: | Recombinant Human CST3 protein expressed by E.coli |
Calculated Molecular Weight: | 15 kDa |
Observed Molecular Weight: | 15 kDa |
Gene ID (NCBI): | 1471 |
Background: | Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration,shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions,establishing its role in vascular disease. In addition,this protein has been shown to have an antimicrobial function,inhibiting the replication of herpes simplex virus. |
Category: | Primary Ab |
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