一抗
二抗
亲和凝胶及免疫磁珠
蛋白质定量试剂盒
蛋白质
规格：
查看说明书| Product Name: | AMACR Polyclonal Antibody |
| Cat No.: | D-AB-10240L |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB 1:1000-1:3000, IHC 1:150-1:300 |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Antigen Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
| Immunogen: | Recombinant Mouse Amacr protein expressed by E.coli |
| Calculated Molecular Weight: | 42 kDa |
| Observed Molecular Weight: | 40 kDa |
| Gene ID (NCBI): | 17117 |
| Background: | AMACR(Alpha-methylacyl-CoA racemase) belongs to the CaiB/BaiF CoA-transferase family. It is a mitochondrial and peroxisomal enzyme that catalyzes the conversion of 2R stereoisomers of phytanic and pristanic acid to their S counterparts. AMACR has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa). However,AMACR expression is down-regulated at the transcript and protein level in hormone-refractory metastatic PCa,suggesting a hormone-dependent expression of AMACR. It has 3 isoforms produced by alternative splicing. Defects in AMACR are the cause of alpha-methylacyl-CoA racemase deficiency (AMACRD) and congenital bile acid synthesis defect type 4 (CBAS4). |
| Category: | Primary Ab |
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