Cat No.: D-AB-10118L

规格：

Product Name:	S100B Polyclonal Antibody
Cat No.:	D-AB-10118L
Clonality:	Polyclonal
Species Reactivity:	Human,Mouse,Rat
Tested Applications:	WB,IHC
Recommended Dilution:	WB:1:500-1:1000,IHC 1:200-1:500
Format:	Liquid
Source:	Rabbit
Purification Method:	Antigen Affinity Purification
Isotype:	IgG
Conjugate:	Unconjugated
Storage:	Store at -20℃. Avoid freeze / thaw cycles.
Immunogen:	Recombinant Human S100B protein expressed by E.coli
Calculated Molecular Weight:	10kDa
Observed Molecular Weight:	10kDa
Background:	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Category:	Primary Ab

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