Cat No.: D-AB-10207L

规格：

Product Name:	JNK2 Polyclonal Antibody
Cat No.:	D-AB-10207L
Clonality:	Polyclonal
Species Reactivity:	Human,Mouse,Rat
Tested Applications:	WB
Recommended Dilution:	WB 1:5000-1:10000
Format:	Liquid
Source:	Rabbit
Purification Method:	Antigen Affinity Purification
Isotype:	IgG
Conjugate:	Unconjugated
Storage:	Store at -20℃. Avoid freeze / thaw cycles.
Immunogen:	Recombinant Human MAPK9 protein expressed by E.coli
Calculated Molecular Weight:	48kDa
Observed Molecular Weight:	46kDa,54kDa
Background:	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Category:	Primary Ab

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