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AFP Polyclonal Antibody

Cat No.: D-AB-10366L
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Product Name: AFP Polyclonal Antibody
Cat No.: D-AB-10366L
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: IHC
Recommended Dilution: IHC 1:300-1:600
Format: Liquid
Source: Rabbit
Purification Method: Antigen Affinity Purification
Isotype: IgG
Conjugate: Unconjugated
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: Recombinant Rat Afp protein expressed by E.coli
Gene ID (NCBI): 24177
Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Category: Primary Ab
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