Product Name: | Galectin 3 Polyclonal Antibody |
Cat No.: | D-AB-10120L |
Clonality: | Polyclonal |
Species Reactivity: | Human,Mouse |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB 1:500-1:2000, IHC 1:150-1:300 |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Antigen Affinity Purification |
Isotype: | IgG |
Conjugate: | Unconjugated |
Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
Immunogen: | Recombinant Human LGALS3 protein expressed by E.coli |
Calculated Molecular Weight: | 26 kDa |
Observed Molecular Weight: | 26 kDa |
Gene ID (NCBI): | 3958 |
Background: | Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis . |
Category: | Primary Ab |
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