Product Name: | PCNA Monoclonal Antibody |
Cat No.: | 2059 |
Clonality: | Monoclonal |
Species Reactivity: | Human,Mouse,Rat,Zebrafish |
Tested Applications: | WB, IP, IF |
Recommended Dilution: | WB: 1:1000-2000; IP: 3ug/sample; IF: 1:100-204 |
Format: | Liquid |
Source: | Mouse |
Purification Method: | Protein A/G Purified |
Isotype: | IgG1 |
Conjugate: | Unconjugated |
Storage: | Store at -20℃. Do not aliquot |
Immunogen: | Recombinant Human PCNA protein expressed by E.coli |
Full Name: | Proliferating cell nuclear antigen |
Calculated Molecular Weight: | 30kDa |
Observed Molecular Weight: | 36 kDa |
Gene ID (NCBI): | 5111 |
Background: | Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. PCNA is a homotrimer and achieves its processivity by encircling the DNA, where it acts as a scaffold to recruit proteins involved in DNA replication, DNA repair, chromatin remodeling and epigenetics. PCNA gene is often stably and constitutively expressed in most tissues and cells, it is commonly used as a loading control for western blot and other test. |
Category: | Primary Ab |
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