Product Name: | NMP22 Mouse Monoclonal Antibody(Clone 5B10) |
Cat No.: | 2031-3 |
Clonality: | Monoclonal |
Species Reactivity: | Human |
Tested Applications: | ELISA |
Clone No: | 5B10 |
Format: | Liquid |
Source: | Mouse |
Purification Method: | Antigen Affinity Purification |
Isotype: | IgG |
Conjugate: | Unconjugated |
Storage: | Store at -20℃. Do not aliquot |
Immunogen: | Recombinant fragment |
Calculated Molecular Weight: | 238kDa |
Observed Molecular Weight: | 238kDa |
Gene ID (NCBI): | 4926 |
Background: | NUMA1, also named as Nuclear matrix protein-22, is a 2115 amino acid protein, which forms multiarm oligomers by association of C-terminal tail domains. NUMA1 resides in the nuclear matrix during interphase. NUMA1 is a highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role and occupies the majority if the nuclear volume. NUMA1 is required for maintenance and establishment of the mitotic spindle poles during symmetric cell divisions, functioning as a tether linking bulk microtubules of the spindle to centrosomes. |
Category: | Primary Ab |
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